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Continuity: In one of the final scenes where Nelson puts himself under, before he injects himself, he doesn't put the suction pads all over his face and chest to track his vitals. Yet when his friends come in, the first thing they check is the EKG machine to check his vitals, which it is displaying. After this, they show Nelson again, and he has the suction pads on his body. How did they get there?
Revealing: When Nelson first undergoes the experiment, the doctors use a small mask to put him to sleep. When he is supposedly waking up, Rachel asks Randy to help her with oxygen. He hands her the same small mask they used the first time ie. anesthetic. Just for a second she has a look on her face which says "this is the wrong mask" and she tries to hide it with her hand. For the whole rest of the film, the other doctors use a bigger mask when giving oxygen.
Continuity: When we first see David, he has an argument with Nelson as he packs his stuff into his truck. At the end of the argument, David pulls the rope down, pulling the canvas tight and closing the back of the truck. There is a shot of Nelson, then back to David who pulls on the rope and closes the back of the truck again.
Factual error: When they jump-start Rachel's heart, she's wearing a bra. As medical students, one of the first things they would have learned is CPR and the use of defibrillators. They should have known to remove things like that or the electricity would have left burns on her chest, particularly where any metal touches.
Factual error: Nelson crosses a vacant street and enters a subway station where he encounters the child ghost that is haunting him. The corner exists, it is called "Six Corners" because three streets come together, and is in Chicago's Wicker Park Neighborhood. However, the train station at that corner is an elevated train, not a subway - this scene is filmed at Damen, Milwaukee, and North Avenues. The real Six Corners is Cicero Ave, Irving Park Rd, and Milwaukee Ave.