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During a lesson on brains, there are two jars with type-written labels ('Cerebrum - Normal Brain' and 'Disfunctio Cerebri - Abnormal). But when Fritz approaches the containers to steal the brain, the labels (Normal and Abnormal) are handwritten. See more...

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In the original ending, Henry Frankenstein dies or is killed before the monster throws him off the windmill.
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After the movie was released into theaters, some scenes were cut because they were too controversial at the time. Scenes like the little girl drowning after the monster accidentally throws her into the water. Henry Frankenstein's line of "It's Alive. It's Alive. It's Alive. In the name of God, now I know what it feels like to be God." was also cut because it was deemed too blasphemous. Also the scene where the hunchback is torturing the monster with a torch was given the axe, as well as the scene where the monster tries to attack Elizabeth (but only in England). These scenes were added back into the film many years later when the movie was re-released on VHS (and later on DVD).
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Universal Pictures originally wanted Bela Lugosi to play Frankenstein's monster since he had done such a great job playing Count Dracula earlier that year. But Bela turned the role down because he did not want to be 'hidden' under all that make-up. Yet 12 years later, Bela would play Frankenstein's monster in 1943 film 'Frankenstein meets the Wolf Man'.
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All of the laboratory equipment was later used in Mel Brooks' comedy "Young Frankenstein."
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