Factual error: At the end when Joe, Brandy, Clem and Charlene, the alligator woman are in Joe's 1967 Plymouth GTX, Robby claims his car is faster. Charlene chides back about his Trans Am, saying 'you think you can match that little old slant six against his 426 Hemi?" Pontiac Trans-Am's did not come with slant sixes, a Dodge motor. His was obviously a V-8, and would have most likely have been a 400, but we get the 'yours is really small' reference.
Factual error: Near the end of the film, during the big shootout scene, there are 2 girls vs. Will Farrell. If you play the movie in slow-motion, you can see that the guns the girls are shooting continue to shoot fire out of the barrel several times, even though the slide is locked back. When a handgun's slide locks back, the magazine is empty. How could they still be shooting when there are clearly no bullets left?
Factual error: The main character, a petite flight attendant, cocks the charging handle on a Mini-Uzi. The weapon had previously fired rounds so her action would eject a live round or in the event of a smokestack jam - a spent shell. Neither happened.
Factual error: When the protagonists arrive to Patmos, latitude and longitude are switched the other way around at 26°489 and 37°411. Moreover, that's not Patmos, but Anydro Patmou, an uninhabited islet unlike what is shown here.
Factual error: The shot of the plane in the Melbourne airport before it took off, and the one in Los Angeles after it lands are of the same place.