Continuity mistake: When Oliver is singing along to "It's Not Unusual" by Tom Jones and is dumping all the pills onto the coffee table, the pills go from being all mixed up to in colour co-ordinated piles, and back and forth.
Continuity mistake: At the start, Summer and Marissa are talking about the weekend. Summer says something like, "I'm going mad over Seth Cohen." The camera swaps from Summer and Marissa. We see Summer first with her hair in front of her ear, then when we cut back after seeing Marissa, Summer's hair has gone to behind her ear.
Answer: He means that if Alex has to go so far as to forbid Ryan from seeing Marissa in order to maintain her relationship with her, their relationship obviously isn't working.