In the beginning as Spyros and his family are landing their boat, Spyros sees soldiers of Argos demolishing the statue of Zeus. In the aerial shots the fishing boat is in full sail. Just as the statue hits the water, the sails are drawn.
Bubo the owl from the original Clash of the Titans makes a brief appearance when the soldiers of Argos are putting together their supplies and arms for the trip to meet the witches. Perseus picks up a staff out of a chest of assorted weapons with a mechanical owl atop of it and asks the Captain "whats this?" the Captain replies harshly "Put it back!"