Factual error: No matter how sophisticated the STEM chip is, it would not enable Grey (Logan Marshall-Green) to go from a completely horizontal position to a completely vertical position in one fluid motion, without bending his knees, and he does this several times in the film.
Revealing mistake: Right at the beginning of the movie, an alien blasts Lieutenant Smalls and he drops his rifle. The weapon wobbles, revealing it's a rubber prop rifle. (00:01:55)
Other mistake: The Space Agency is trying to use an android mechanism (Human 2.0) to go to The Void and make first contact. Their first attempt at putting a human brain into the android fails. The solution is to make the android mechanism imprint human cells to facilitate the brain/android connection. The Agency is up against a time constraint, and someone comes up with the idea of using military Humans 2.0 to go on the voyage. Wait a minute! So now we learn there are other Humans 2.0 in existence? Wouldn't whoever made those already know how to solve the human brain/android interface? Why is the Space Agency reinventing the wheel? (00:40:55)