Corrected entry: At the end of the episode, when Sheldon imagines going to the Grand Canyon to scream about Leonard, that's not the Grand Canyon, signs not withstanding. The location is Dead Horse Point State Park in Utah (near the town of Moab), with the view looking roughly south into Canyonlands National Park. [GPS near 38°28'12" by 109°44'30".] It's several hundred miles upriver from the Grand Canyon. [At least it is along the Colorado River.] The first national park sign looks authentic, but the small one at the overlook is fake, since that's not the Grand Canyon. And by the way, since it's just after New Year's, there would likely be snow at both the Grand Canyon and Dead Horse Point; the images used are not winter scenes.
Factual error: There is not a snowball's chance of Howard becoming an astronaut. He suffers from cardiac arrhythmia, something about which he is completely open. "Transient" or not this is easily detectable by a simple electrocardiogram, which is a fundamental part of the many medical examinations a potential astronaut will have to pass. He wouldn't even be allowed to start basic training. Note also that during his basic training he shows signs of severe stress and trauma which would inevitably trigger a cardiac episode. Even if it didn't the fact that he was falling apart at the seams would have him removed from the programme for his own good.
Trivia: In this episode, Sheldon and Amy are trying to decide on couples' themed Halloween costumes. Sheldon is standing in front of the dry erase board. There are 2 columns written on the board. One named "Couples I Like" and the other "Couples You Like." Under the "Couples You Like" column, one of the couples is Blossom and Joey. Blossom is the name of the television character played by Mayim Bialik in the 90s and Joey was one of her brothers.
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