Benediction - S3-E21
Corrected entry: Holtz has Justine kill him by puncturing his neck to make it look as if Angel bit him. When Connor finds them, there is very little blood coming from the wound, which WOULD be the case if Angel had bit him because a vampire DRINKS the blood, so what did Justine do with it all? (00:42:05)
Correction: Unless you hit a major artery like the jugular, a puncture wound to the neck will leave some blood but not gobs of it - ask any ER doctor. The ice pick probably hit Holtz's spine severing the nervous system; after all, it's not like Connor's going to do an autopsy.