Continuity mistake: Just after Chandler has used the chapstick, in a shot from the side the stick is in his right hand, and then in the next shot he is instantly putting a tissue (which wasn't visible before) up to his lips, and the stick has moved to his left hand.
Continuity mistake: When Frank Jr is sitting in front of the TV while Davey and Goliath is on, his hand is along the edge of the TV set; however when Phoebe walks in, his arm is straight out. Then when Mrs Knight comes in, his head is straight down and the arm is back along the edge.
Factual error: When Pete takes Monica to Rome for the date this would have been impossible as Rome is 6 hours ahead of New York and at least 4/5 hours travel time, assuming they went by Concorde (double that otherwise). They would have had to have left New York early in the morning to make dinner for 8/9 pm in Rome.