Gru: Goodnight Margo. Whoa, wait, hold your horses, who are you texting?
Margo: No one, just my friend Avery.
Gru: Oh, Avery, wait. Avery, is that a boy's name or a girl's name?
Margo: Does it matter?
Gru: No, no, it doesn't matter, Unless it's a boy!
Lucy jumps from the airliner and flies her hang-glider straight to Eduardo/El Macho's Cinco de Mayo party to find Gru. How did she know Gru would be there? He had no intention of going and only did so after he was pestered into it by the girls on the very night of the party, so he couldn't have told her himself. Shouldn't she have gone to his house instead?
In the end credits the minion that is causing the screen to drop has "Heterochromia iridum." His eyes are two different colors.