Revealing mistake: When Jessica Alba is in the dentists room with the chipped tooth, it's very obvious she's wearing a set of false teeth over her teeth.
Deliberate mistake: In Antarctica when Charlie and Cam kiss, their tongues become froze together but this is impossible as it would take a freezing object for this to work.
Other mistake: When Chuck is driving Cam to get her spare set of keys you can see it is dark out and the car has its headlights on, but the taillights are out. (00:25:50)
Continuity mistake: Jessica Alba's bent thumb is shown as straight in a later shot showing her receiving a band aid as a present.
Continuity mistake: While Chuck and Stu play Frisbee at the park, the sun changes between shots.
Continuity mistake: At the beginning while Chuck is kissing the blonde girl at the beach, the sun changes between shots.
Continuity mistake: When Chuck leaves his home in order to look for Cam at the airport, he is wearing a gray T-shirt, then suddenly in the car he wears a long sleeve shirt.
Continuity mistake: During the scene when Charlie is playing the Xbox 360 his friend comes in and he puts down the Xbox controller, but it changes position between shots.
