Trivia: There have been some problems with the shooting of the rat scene in the Istanbul sewers. At first, white lab rats were considered. In order to make them brown, they were coated with chocolate powder; but the rats found the substance too delicious and spent their shots licking each other off. Finally, real rats were used, but they went amok in the studio. Sean Connery relieved the situation by simply opening the door.
Trivia: During the chess game between Kronsteen and McAdams, the position that appears on the board was taken from a real game played between Boris Spassky and David Bronstein in 1960, the game is well known amongst chess players all over the world, Spassky won the game in brilliant fashion, and it was his actual moves that Kronsteen plays during the end of the game.
Trivia: It's mentioned elsewhere that Pedro Armendáriz had terminal cancer and committed suicide shortly after filming his scenes. However, he was determined to finish his role in the film first in order to provide for his family. During the scene where Bond shoots Krilencu for him, and Kerim Bey uses his shoulder to brace the rifle for Bond, Sean Connery was actually holding Armendáriz up so that he could complete the scene.
Trivia: Peter Burton, who played Major Boothroyd in "Dr No", was unavailable for this film, so Desmond Llewelyn replaced him. Llewelyn's name does not appear in the opening title sequence and is reserved for the closing credits, where he is credited as "Boothroyd." The character is not referred to by this name in the film, though M does introduce him as being from Q Branch.