Plot hole: Lois and a friend of hers are watching Non and Superman fight. But this is totally senseless, because Superman had been flying around Metropolis and chances are slim that he appears in the very same spot to let Lois watch him. And, second and most important, should any doubts arise, the panning angles of the camera never show Lois's building, with the big broken window and the flag poles.
Plot hole: When Superman becomes human for Lois, the molecule chamber nearly rips him apart, he suffers. At the end of the movie, when he tricks out of the evil 3 and turn them into humans with the same radiation, they are just looking around, wondering about the strange lights, but don't suffer at all.