Plot hole: How does the little girl Nina know Ferdinand's name if only the animals can communicate with each other? They're all calling him Ferdinand before she "names" him that.
Continuity mistake: The amount of ketchup and mustard on the prison chef's apron changes between shots.
Continuity mistake: Before the race in Thomasville Cruz has the 20 number only on her right side but later she has the number also on her left.
Continuity mistake: When Tim and the baby are tugging over the tablecloth, Tim's meal and drink have vanished from the table.
Continuity mistake: When they jump in the pool, they drop the guitar. When they jump out their guitar is no longer in the pool.
Continuity mistake: Gene and High Five are using costumes to hide, and Gene's costume leaves a spike in his face, but when they put the costumes down and run around the corner there is nothing on his face.
Other mistake: When Captain Underpants falls in the Turbo Toilet 2000's mouth which has a liquid in it, he doesn't turn into Mr. Krupp.
Continuity mistake: Batman plans to put the Joker in the phantom zone, and Barbara says no. She is still right in front of the SUV, but in the next shot, she is suddenly standing more forwards.
Continuity mistake: Gargamel finds out of the smurf he captured is Smurfette. She grabs the bars of the cage, but the position of the door hinges changes, switching from her right to her left, back and forth. (00:13:35)
Continuity mistake: Overgirl kills Dollman by blowing a huge hole through his chest with her laser vision, and he falls back behind the other Freedom Fighters. They turn to look at her which would put him directly behind them. As Overgirl is hovering down and confronting them it cuts to a shot of them from in front, and Dollman's body has vanished from behind them. (00:08:45)
Continuity mistake: Sara recovers the artifact and gets on the boat. She removes the deep-dive helmet and the oxygen tank. The villain is looking at her through his binoculars, she hasn't moved, but the equipment she took off and dropped on the deck has vanished. (00:03:00)
Continuity mistake: When Mariah is talking to the girls on the bridge at the beginning of the movie, the girl in green is holding her leash (her dog's that is) with her right hand in the shots from behind, the left hand in others including the wider ones from the protagonist's height. (00:02:25)