Trivia: When Britt Reid is flicking through Kato's sketch book you see a sketch of Bruce Lee. Bruce Lee played Kato in the original Green Hornet from 1966-1967.
Trivia: The final chess match between Moriarty and Holmes is based loosely on a famous chess match between chess masters Bent Larsen and Tigran Petrosian. The match involved the sacrifice of a queen and a surprise checkmate, thus mirroring Holmes' apparent sacrifice of himself to stop Moriarty.
Trivia: Eddie Murphy and Chris Rock were both considered for starring roles in this film at one point, with the film being developed as an "African American Ocean's Eleven".
Trivia: In the coffee shop scene at the beginning, the cashier/server who waits on Daniel Craig is the daughter of Michael Nyqvist, the actor who played Mikael Blomkvist in the Swedish version of this film.
Trivia: Olivia Wilde plays Justin Timberlake's mother in the movie, even though she is three years his junior.
Trivia: Despite relatively high billing in the opening credits, Stana Katic only has about five minutes of screen time.
Trivia: Whilst filming his death scene on the beach, Ron Perlman shattered his kneecap when a wave hit him.