Best sci-fi movie plot holes of 1966

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Fantastic Voyage picture

Plot hole: Even if the white blood cells will attack and destroy the sub and the body of Doctor Michaels the atoms would still remain and take normal size after the critical 1 hour is up. This would also apply to the laser gun which they forgot or left behind on purpose, as well as several dozen litres of saline solution which were miniaturised and pumped into Benes' body. He's in a lot of trouble.

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