Visible crew/equipment: Opening credits (also a few minutes in) has a fiery spaceship crashing into the camera for this was a 3D movie. What's interesting is that a mirror can be seen on the left portion of the screen just before the collision. This was apparent at the theatres and on the VHS tape release. For some reason, the DVD release has it cropped out and now the spaceship is off-centered at the beginning (fortunately the bonus material still shows it). (00:00:20 - 00:03:50)
Continuity mistake: When the Beast first tears down the streets of New York, a lone police officer empties his service revolver at the beast before being eaten. A few minutes later, a group of a half dozen police officers pump their shotguns before firing at the beast - the officer who was already eaten after firing his revolver can be seen alive in the far left of the screen as one of the officers readying his shotgun.
Character mistake: On the sign outside Dr I.Q. Hi's headquarters, the word "Stratosphere" is spelled "Stratopere."