Revealing mistake: When Mr. Peabody is fishing, it is obvious that he is in a boat on the floor of a studio. Rear-screen projection is used to show the ocean behind him, but while he is standing in the boat and trying to reel in his catch, the boat is absolutely motionless.
Revealing mistake: When Tom is punctured in the rear by the fork that Nibbles is holding, his tail is missing.
Revealing mistake: When Potter starts shaving at the morning of the Indian attack on the wagon train, his mirror falls off the post, and as he bends down to retrieve it, an arrow embeds itself right above his head. If you look closely in that scene, you can see a length of targeting wire used to guide the arrow sticking to the post above Potter's head. (00:37:10)