Factual error: Michael and Lincoln are seen in the morning at 9 am in Montana (between Great Falls and Helena). Later in the show, the next day at 12.50 am, they are trying to meet with Sarah in Akron Ohio. That is a 33-hour drive from Helena.
Continuity mistake: When Michael is sitting in the park he's staring at the front page of the newspaper. As the camera follows a man in the park you can see that Michael has opened to the midpages, but in the next shot Michael is looking at the front page again, before opening it another time. (00:02:00 - 00:02:30)
Factual error: There is no prison in the United States that does not strictly segregate Death Row prisoners. They are never, ever allowed contact with the general prison population.
Rendezvous - S2-E10
Continuity mistake: Season 2, Episode 10 "Rendezvous". When Geary hits Bellic then backpack with money falls. In the next shot, before Geary hits Bellic second time we see that the backpack is standing.
Other mistake: If the show takes place in May, when Lincoln is scheduled to be executed, why is it snowing?
Suggested correction: It does occasionally snow in such months. There is no rule about weather being certain. It's just what we consider usual for each season, e.g. winter = cold. Characters even comment on very "variable" weather in state.
Other mistake: Michael goes to Fox River in April. Maricruz gets pregnant in the same month. In mid-June, when Michael get arrested in Panama, she's still pregnant. That's 2 months. He was in there for about 2 weeks, due to his deal with the company. Therefore, he would have escaped Sona at the end of June or the start of July. The start of Season 4 is set 3 weeks after the escape from Sona, so Maricruz should be 3 months pregnant, but gives birth at the start of season 4, meaning that the baby is 6 months early but looks very healthy.
Continuity mistake: Season 2, Episode 10. When Michael and Sara are driving towards Mahone down Butterfield Road, both cars are seen in one shot and both cars are on a gravel road. In the next clip, seen from Mahone's end of the road, his car is on asphalt.
Factual error: Episode: Bad Blood. When the airport security guard stops to give Sucre a ride, his car has Sinaloa plates on it. Since he works in Ixtapa/Zihuatinejo, it should have Guerrero plates on it. Sinaloa is several hundred miles away.
First Down - S2-E4
Continuity mistake: During the car chase in the beginning of the episode, Bellick's car swerves to avoid hitting a truck as they go over a bridge. The next shot is from in front of the cars, and in the background you can see the bridge and a stretch of road behind it, but the truck has vanished. (00:02:40)
Revealing mistake: When Haywire jumps off the tower, it's obviously a stuntman falling down. And when you see his fall from above, he is falling towards a big drain. But when the scene cuts to the part when he has landed, he's lying on concrete. (00:42:15)
Revealing mistake: In the episode where Scofield, Sucre and T-Bag are driving in Panama, the trees in the background have no leaves - like Autumn/Winter in the US. And even though there of course are trees in Panama which shed their leaves, there is no time of year when all trees are leafless - like in the temperate zones. That shot was definitely not filmed in Panama.
Continuity mistake: This happens in the scene where Lisa is scolding LJ for getting arrested. When LJ says "I don't have a father", he is leaning on the table with his arms crossed. When the shot changes, his arms are uncrossed and in a completely different position. (00:22:25)
Other mistake: The psychologist shows Michael a photo of his family with his Mom, Dad, Michael and Lincoln but Michael never actually met his father when he was young.
Revealing mistake: When Sara crashes into the ATV to save Michael, you can see that the people on the ATV are switched out with crash-dummies.
Continuity mistake: Series 2 - Episode 10. When Sara is to meet Michael at 1681 Butterfield Road Sara looks in the mailbox. She closes the lid, yet the mailbox is seen standing with the lid a bit open. In the next couple of shots the mailbox is completely open, and when they jump in the car and leave, the lid is now closed.
The Message - S2-E15
Factual error: When Fernando Sucre steals the Volkswagen in Sinaloa, Mexico, the license plate on the front begins with F. All Sinaloa passenger plates begin with V. (00:14:10)
Revealing mistake: In the final scene you can see Abruzzi in his cell where they have reused shots from series 1 in Fox River.
And Then There Were 7 - S1-E11
Continuity mistake: When chasing LJ through the woods, Quinn's wounds go from his right side to his left side and back. (00:29:10)
Audio problem: Bellick gets shot in the leg and screams but in the brief shot we see his face during the sound, he isn't screaming at all. (00:23:20)