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House, M.D.
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Sports Medicine - S1-E12

In this episode the director, Bryan Singer, makes a cameo as the director of the sports documentary Hank Wiggen is starring in.

Hugh Laurie auditioned for the role as Dr. Gregory House in his hotel room bathroom in Namibia. He was rehearsing his role for the film The Flight of the Phoenix and claimed that the bathroom was the only place with enough light. He also apologized for his appearance on tape before the audition as he'd just come back from filming. The fact that House has a somewhat scruffy and unkempt look, particularly his constant five o'clock shadow, has been attributed by creator David Shore to Laurie's appearance in this audition tape.

Histories - S1-E10

The $100 bill that House tries to bribe the cop with is fake. The portrait of Ben Franklin is facing the wrong way.

Bryan Singer was looking for an American actor to play House and when he saw Hugh Laurie's audition tape said that he had found his American actor. Hugh Laurie is in fact British.

Histories - S1-E10

Victoria's drawing of "Kaplow's Pawn Shop" is an in-joke reference to writer and producer Lawrence Kaplow.

The diagnosis of Lupus appears to be a running joke throughout the series - it is commonly suggested as a possible illness, but is always dismissed. In one episode, House hides his Vicodin in a book on Lupus, stating that 'it is never Lupus'. In another episode House has a janitor stand in for his three assistants (who left at the end of season 3). The janitor suggests Lupus as a possible diagnosis - inevitably he is wrong.

Clueless - S2-E15

The programs on House's TiVo include "the OC" and "Spongebob". He also has a few episodes of "Blackadder", a show which featured Hugh Laurie.

During a guest appearance on The Tonight Show on 16 November 2005, Laurie revealed that he took the highly-addictive painkiller Vicodin in order to get into character for his role as Dr. House.

Jesse Spencer, who plays Dr. Chase, grew up in a family of Doctors. His father and two brothers are doctors while his sister is going through med school. When they see one of the episodes they not only try to figure out the cause before him but note all his medical mispronunciations.

The character of House is based on Sherlock Holmes. Both suffered drug addictions (House - pain killers, Holmes - cocaine). Both focus on the patient/criminal's motives and actions rather than physical evidence. Neither can cope with normal society and have sociable sidekicks (Wilson and Watson - Dr. Wilson actually gets called Dr. Watson once by a patient in the first series). Both are extremely lazy when not on a case (Holmes read the agony aunt columns in the paper, House watches Soaps). Both never call anybody by their first names and finally both live at No 221B.

Joy to the World - S5-E11

This episode contains another reference to Sherlock Holmes. Wilson tells the (fictional) story of who had sent House a present. Wilson says it was one of House's first patients called Irena Adler. He then explains that House had feelings for the patient, but did not take it any further and therefore regards her as the 'woman who got away'. Irene Adler was an adversary who bettered Sherlock Holmes - the woman who got away. As it happens, the fist patient House treats in the pilot episode is called Rebecca Adler.

No Reason - S2-E24

This episode contains a further example of the link between Sherlock Holmes and House. The former patient of House, who shoots him, is called Jack Moriarty. Prof. James Moriarty is the arch enemy of Holmes.

Autopsy - S2-E2

Elvis Costello recorded the song "Beautiful" especially for this episode. Mentioned by David Shore on the DVD.

Fidelity (aka: Truth or Consequences) - S1-E7

On the TV after House finishes watching his soap, its credits are rolling. Most are made-up names but two are in-joke references to staff members. Marcy Kaplan as Hair Stylist - usually credited as Marcy G. Kaplan, she was an Associate Producer for that episode and is now a Co-Producer. And Cindy Carr as Wardrobe - she was a Set Decorator for the entire first season except for the Pilot.

Poison - S1-E8

Mrs. Miller mentions that she can't stop thinking about Ashton Kutcher. Coincidentally, John Patrick Amedori, who plays Matt Davis in this episode, also played a young Ashton Kutcher in the 2004 movie, The Butterfly Effect.

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Quotes

Dr. Foreman: You really want to screw Whitey? Be one of the few black men to live long enough to collect social security. Take the medicine.

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Mistakes

As House describes the lady's symptoms, in the front shot Chase has a small book/pamphlet in his hand. The camera changes to a side shot in the middle of House's description and suddenly the book is on the table and no longer in Chase's hand. This happens right in the middle of House's line and Chase doesn't make any quick movements to account for this discrepancy.

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