Factual error: Season 2 Episode 1 - Acceptance: When they do the MRI on the death row guy, House says that the ink will get sucked out due to the strong magnet. This is incorrect; the only thing that can happen is a bit itchiness or skin irritation.

Plot hole: When Wilson does an ultrasound to check for cancer in Alex' ovaries he fails to notice the fact that she doesn't have a uterus. If he mistook her bladder for her uterus, which sometimes happens, she would have appeared to be missing her bladder instead. Yet Wilson doesn't pick up on anything being missing.

Continuity: About 5 minutes in, when Foreman struggles with opening the coffee package, House rips the entire top of the package off with his teeth. In the following shots, you can see that the coffee package merely has a corner ripped off.