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ER

Doug Ross frequently hung his head low, appearing ashamed or thoughtful or privately amused, depending on the scene. This wasn't just an element of the character: George Clooney had taken to writing his lines on papers, sheets, and other props.

Every episode has the patient list by the nurse's station. On the patient list, different names are mentioned, like Marguiles or Tierney. They put these names there as a spoof of the show.

It is finally revealed (11-14: Just As I Am) that Dr. Weaver uses the crutch because of congenital hip dysplasia.

Reformed Dispatcher

Chaos Theory (a.k.a. Unknown Origin) - S9-E1

The character of Haleh was supposed to appear in this episode but was written out, and with good reason. This episode picks up right where the previous season's finale left off, but the actress who plays Haleh had lost over 100 pounds over the summer hiatus.

Ambush - S4-E1

In the live broadcast of 1997, the baseball game that George Clooney's character is watching in the break room was the Cubs-Astros game, also being broadcast live that night on WGN.

24 Hours (1) (a.k.a. The Longest Day (1)) - S1-E1

The first four episodes of the show all began the same way - with one of the doctors being awakened early in the morning from 'Exam 8' at the end of the hallway, in this order: Greene (Pilot), Lewis (Day One), Benton (Going Home), Carter (Hit and Run). Ross (George Clooney) was the only one of the original five who never slept in Exam 8.

Secrets and Lies - S8-E16

In this episode, Kovac mentions that he played Hamlet at home in Croatia. Goran Visjnic, who plays Kovac, was discovered by a casting director for ER while playing Hamlet with the Croatian National Theater in Zagreb.

Freefall - S10-E8

In "Freefall" as Dr. Romano and Neela are going up the elevator to return the forgotten watch, the Musak playing is "Freefalling" by Tom Petty and the Heartbreakers. Fitting.

Nikki

Ambush - S4-E1

If anything had gone wrong during the broadcast of the live episode, e.g. a technical failure or forgotten dialogue; the producers had additional actors ready to improvise a scene that would have been inserted to cover. This was never used.

Just As I Am - S11-E14

Frances Fisher plays Laura Innes' mother in the episode, even though in real life she's only five years older than Innes.

Going Home - S1-E4

Madame X, the patient who nobody knows which doctor is treating her, is played by George Clooney's aunt Rosemary.

Cubs Fan

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Quotes

Robert Romano: I haven't seen you in, oh gosh, who really cares?

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Mistakes

As Mark futilely pounds on Jodi O'Brien's chest, Carol can be seen in the background, removing her protective glasses with one hand. However, after the time of death has been called and they're showing the reactions of everyone present in the room (Susan, Carol, Carter, Lydia, Chen), Carol is seen taking the glasses off again, this time with both hands.

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