Other mistake: During the scene (towards the end of the episode) when Horatio's young wife Marisol dies, there are two worthy mentions. First is when we see Horatio walk into Marisol's room, there is a doctor present but the two do not speak. Horatio speaks to Marisol at the side of her bed and they joke about their supposed date later that night, and her speech seems fine. A few seconds later while holding her hand, we hear the "flat line" and Marisol passes away. About two seconds after we hear the flat line, the camera angle shows Marisol still turned toward Horatio, her chest still moving to breathe. A split second after that though, the camera angle now shows Marisol face up in the bed, presumably dead. Second issue and perhaps most importantly - Marisol was young, and a gunshot victim who had been in stable condition just the day before. Even if her condition had turned more critical, it seems almost impossible that as soon as she flat lined, there still would not have been immediate resuscitation attempts or calls for a resuscitation team, especially with a doctor who was already in the room.
Death Grip - S2-E4
Other mistake: While irrigating the alligator's stomach a human foot falls out, there is no way a foot that size could fit through that PVC pipe.
Other mistake: The hotel manager is charged with negligent homicide because he was using propane without the additive, but the victim was knocked unconscious. The additive wouldn't have made a difference.
Death Grip - S2-E4
Plot hole: There is absolutely nothing that would give Horatio any reason to think the severed arm they found was from a previous victim of their suspect. It doesn't make any sense he would pick something as random as the arm that has no connection (other than it being found during the search for the girl) to the case.
All In (2) - S6-E16
Continuity mistake: The body is discovered by two teens fishing with explosives and an arm comes up in the water. When they pull out the body that was inside a car, the victim has both arms tied up to the wheel and at the morgue she is missing one arm. We can even see the doctor cut the tape off the wheel and the victim's wrist to expecting to find prints on the inside of the tape.
Plot hole: The whole scenario is fake and everyone at the bar is an actor, so why would they call the real cops.
Suggested correction: To specifically get the cops involved so Neal feels more in danger. LIVE Corporation basically filed a false police report, which Wendy Colton said the cops can talk to the company's lawyers about.
Miami, We Have a Problem - S8-E15
Factual error: Ryan is stated to have a BS in organic chemistry, working on his Masters in Genetics when we first meet him. When Travers tells him the shuttle was leaking oxygen, Ryan corrects him and says "air", to which Travers has to correct him. ANY gen chem student learns that "air" is a mixture of oxygen, nitrogen, water, and a few other trace gases such as helium and methane. This is a pretty big blunder for someone who supposedly holds advanced degrees in Organic Chemistry and Genetics.
Delko for the Defense - S8-E11
Other mistake: Horatio: "Eric, the forensics expert cannot get cold feet." There was absolutely no reason for Eric to be nervous. IF he'd been a CSI all this time, he would be in court testifying about his evidence on a regular basis. CSIs ARE the forensics experts.
Factual error: CSIs in real life are not police detectives, nor are they beat cops. Crime Scene Investigators are just that: they're regular people, some with 4-year-bachelor's° in STEM fields, others completing Criminology Associate's degrees, who are ONLY responsible for investigating and gathering evidence at crime scenes and then serving as expert witnesses in court. In fact, they spend more time in court testifying of the evidence they collected than anywhere else. They don't interrogate suspects, nor do they chase them down and arrest them.
Factual error: In Natalia Boa Vista's backstory, she states she knew Horatio from her "work with the FBI." But not all FBI agents started as LEOs (law enforcement officers). In her whole time as a CSI, she wields a badge, makes arrests, and interrogates suspects just like a cop (the ONLY 3 characters we know for certain that were LEOs were Calleigh [the flashback episode with Horatio and Jesse], Eric [the flashback episode when Horatio tells Eric to "come see me when you finish the academy"], and Ryan Wolfe, who's fresh off beat patrol when he joins CSIs). In this episode she tells Calleigh she's late to her crime scene because she just picked up her new sidearm and "now I can back you up on crime scenes!" BUT, if she were already a cop she would have been issued a firearm upon graduation. Thus, Natalia (and Walter) were never cops. This show took severe liberties with reality. Real CSIs are no more than expert witnesses, NEVER given the responsibility of arresting or interrogating suspects.
Open Water - S4-E22
Continuity mistake: At the onset of the episode, we see the overview of the cruise ship with full sunlight, many women sunbathing on the deck, and people/staff walking around. We then hear "man overboard", and everybody on the ship's deck takes notice. Various people, including the ship's captain and the man's wife, then attempt to help the man to no avail. A few minutes later in the episode, Horatio and Delko are questioning the ship's captain about what happened and asked him about witnesses, etc. The ship's captain said "he didn't think that there weren't any witnesses around, as this happened around 6am." The ship's captain would have no reason to lie at this point, so this was totally inconsistent with the events shown just a few minutes earlier.