Other: When Peter is painting the Sistine chapel, he has blue paint on his brush, even though the picture is entirely black and white.

Other: During the Vagina Monologues show, the pair of legs casts a shadow but the microphone stand doesn't.

Continuity: As Brian is saying "OK, you know what, fine, you are a genius", the glass of water disappears.

Deliberate "mistake": In season 4 episode 7, 'Brian the bachelor'. Cleveland is sitting in a chair in a waiting room and is getting really nervous. Peter tries to help him by tying him to a chair and when that doesn't work, he takes off all of their clothes. Peter ties Cleveland's hands to the arms of the chair and then takes Cleveland's clothes off. He couldn't have taken the shirt off while Cleveland's hands were tied to something without untying him or ripping the shirt, which he didn't do.

Continuity: When Chris is sitting on his bed talking to Doug, the squares on his quilt pattern get smaller.

Continuity: Just after Lois decides to get rid of Chris's pimple, the pimple changes position in relation to Chris's hair.

Continuity: When the Griffins are discovered by Joe, Peter switches from his Sumo outfit to his regular outfit in a matter of seconds.

Other: When Stewie is playing Simon Says, the sequence Stewie plays is different than the one that the Simon Says played. If he played it wrong, there should have been a sound from the Simon Says indicating that Stewie played it wrong.

Continuity: Osama bin Laden's dialysis machine disappears after Stewie knocks him down.

Continuity: When the Griffins are driving to Washington we see a faraway shot of the car driving from left to right. Peter and Lois are in the front and Chris is leaning back on the back seat. In the next shot, Chris is leaning forward against the back of Peter and Lois's seats.

Continuity: When Chris is saying "I'm not supposed to tell Mom cos she'll just bitch about it" there is a door behind Lois with a box next to it. In the next shot there is a smaller box next to that box which was not there before.

Continuity: After "Herbert the Pervert" leaves the Griffins' house, the size of the couch in relation to Chris changes distinctly between shots.

Other: When Mr. Hubert is singing about his fantasy life with Chris, he is reflected in a mirror but his arms do not have the same angle; the reflected one is much steeper.

Continuity: When the baseball crashes through Herbert's window, the glass shards are in different places in different shots.

Continuity: When we first see all the guys at the NAAFP meeting, there are two guys in the top right corner; one with a singlet and one with brown hair and a green-brown T-shirt. In the next shot, these two guys come in from the opposite side of the screen.

Continuity: Just after Patrick 'kisses' his imaginary girlfriend goodbye and tells Brian to look after her, Brian switches position on the couch. In the first shot he is sitting on a crack between couch pillows, but in the next shot he is sitting in the middle of the centre pillow.

Continuity: After Joe shoots a hole in the table, the hole changes size.

Continuity: When Lois turns on her parents' bedside lamp, it only casts a small beam of light onto the floor, but later in that scene, the same beam of light is much bigger.

Continuity: When Francis is standing on a chair, nailing the crucifix above the door, the bottom of the crucifix overlaps onto the door frame, but when Francis comes down from the chair, the bottom of the crucifix is above the door frame.

Continuity: When Francis arrives, he changes from standing on the threshold to standing inside the house, even though he could not have moved between shots.