Continuity mistake: When the Stonecutters are singing "We do", the position of several characters, particularly the Martian and Chief Wiggum, change randomly as the camera angles change. The Martian starts at the end of the table on the right side, with Chief Wiggum two seats to the left of him. In later shots, the Martian, then Wiggum are both switched to the same position, midway up the left side. Then, when the song ends, Wiggum has disappeared, and the Martian remains in this new position.
Continuity mistake: When Burns first shows the team the nerve tonic, the "&" on the 'Brain & Nerve Tonic' label is facing backward, but as Burns pulls it away it faces forward. Then as he moves it around as he's talking, the "&" switches between facing forward and facing backward again. This happens all in the one shot.
Continuity mistake: In Hungry are the Damned, when The Simpsons are on the spaceship and the aliens show them the food, there are 3 pots and two plates. Yet when the shot changes there are 4 pots and no plates.
Continuity mistake: When the Simpsons are eating and the family are praising Marge, Homer's plate is first seen to have a small amount of yellow food and a bit of pink food (meat?).In a later shot when Homer steals and uses Marge's pepper spray he has a large pile of yellow food.
Continuity mistake: In "The Thing and I": After the kids have found Hugo in the attic, when Marge and Homer return home, both front door knobs (inside and outside) do not have backplates, but once Hugo escapes both door knobs have backplates. The two backplates vanish and reappear repeatedly in following shots. It's funny because when they leave to search for Hugo, Homer shuts the door with no backplates, but then Bart uses a key in the backplate to lock the front door.