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Entry Lisa Kudrow was originally cast to play Roz Doyle but was replaced with Peri Gilpin before filming began.
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Entry David Hyde Pierce has been Emmy-nominated for his portrayal of Niles every year since 1994 (winning in '95, '98 and '99) for Outstanding Supporting Actor in a Comedy Series.
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Entry David Hyde Pierce made a guest appearance on "The Simpsons" as the brother of Kelsey Grammer's character Sideshow Bob.
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Entry Frasier was not originally meant to have a brother. But the show's creators saw David Hyde Pierce and realised he looked remarkably like a younger Kelsey Grammer. So the character of Niles was created especially for him.
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Entry The last 3 initials of the radio station, KACL, are taken from the creators' names, David Angell, Peter Casey, and David Lee.
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Entry It's probably just as well that Lisa Kudrow didn't get the part of Roz considering she and Frasier met before in an episode of Cheers when she played a character called Emily who was giving Woody acting lessons. Submitted by omegaman3000

Leapin' Lizards (series 3)

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Entry When Bulldog calls up Frasier and asks him if he can sing a bit, Frasier stars singing the Gilbert and Sullivan song "Three Little Maids from School" which of course leads to great embarrassment. In the episode "Cape Fear" from The Simpsons, Kelsey Grammar guest stars as Sideshow Bob and also has bad luck with Gilbert and Sullivan music. Bob gets badly injured after the family sings the Three Little Maids song. Later he is asked to sing the score from the HMS Pinafore and it foils his plan. Submitted by Lummie

Head Game (series 4)

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Entry At one stage, Niles refers to Frasier's 'Big red clown shoes'. Kelsey Grammer provided the voice for Sideshow Bob in 'The Simpsons', a clown character who wore such shoes. In fact, in the first episode Kelsey Grammer's voice was used, those shoes were key to the plot.

Halloween (1) (series 5)

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Entry In the party, Frasier is continually interrupted whilst trying to get to know a blonde woman named Eve. Eve is played by Camille Donatacci Grammer, Kelsey Grammer's wife. Submitted by Lummie

Something Borrowed, Someone Blue (2) (series 7)

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Entry Two endings were filmed for the last episode of season seven, one in which Daphne and Niles ended up together and one in which they didn't. It was then up to the audience to decide which version they liked better.

Something About Dr. Mary (series 7)

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Entry In this episode, Roz is replaced as Frasier's producer for a short time by a lisping character named Chuck Ranberg. This was the actual name of one of the show's writers and co-producers from 1993-1997 - shows from those years list him in the credits.

It Takes Two to Tangle (series 8)

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Entry In the opening credits Niles mentions that Daphne had lost 9 lbs. 12 oz at the weight-loss spa. This is probably a deliberate reference to the birth of Janes Leeves' (Daphne) daughter. According to www.imdb.com, she was born in Jan 2001 and weighed 9 lbs. 12 oz.

Hooping Cranes (series 8)

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Entry While Niles makes his basketball shot on the first attempt, at the stadium it took actor David Hyde Pierce 27 attempts to do it.

Goodnight, Seattle (2) (series 11)

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Entry Niles and Daphne's baby, David, was named in memory of show producer David Angell, who was killed in a plane during the September 11th attacks.
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Entry Despite the episode's visual joke about Bebe's plastic surgeon, at the time of writing the actress is only 49 - the same age as Kelsey Grammer.

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