Continuity mistake: In the scene where Data is brushing Timothy's hair into a copy of his own hairstyle, he stops, kneels down and asks Timothy "Timothy, are you having bad dreams?" In this shot there is a big tuft of hair on the right side of Timothy's head that sticks straight out. When their conversation is over and Data stands up in the wider shot, all of Timothy's hair is in place.
Continuity mistake: When commander Data is reciting the code to lock the rest of the crew out of the computer, he states the code '1-7-3-4-6-7-3-2-1-4-7-6-C-3-2-7-8-9-7-7-7-6-4-3-T-7-3-2-V-7-3-1-1-7-8-8-8-7-3-2-4-7-6-7-8-9-7-6-4-3-7-6-LOCK', but when the computer screen is shown the code reads '1-7-3-4-6-7-2-1-4-7-6-C-3-2-7-8-9-7-7-7-6-3-T-7-3-2-V-7-3-1-1-7-1-8-8-8-7-3-2-4-7-6-7-8-9-7-6-4-3-7-6-LOCK.'
Character mistake: When Troi is talking with Picard and Dr. Crusher about what's wrong with her mother, she says that "something was happening in her metaconscious mind." Dr. Crusher then asks "metaconscious?" As a Star Fleet doctor, she's had to study the neurology of Betazoids, Vulcans, and other telepaths. She should be familiar with the concept. (Yes, it's expository dialogue for us, the audience, however, Picard is in this scene too and it would have made more sense for him to ask about it.)
Plot hole: After Picard, Guinan, Ro, and Keiko all beam back to the ship and have been transformed into children, their clothing hangs loosely on all four. Later, Dr. Crusher even states "But as far as we can tell, only their bodies were changed". Presumably they replicate a change of clothes that fit before the next scene. However, no one on the medical team addresses the fact that the now pre-pubescent Captain Picard has an adult-sized parthenogenetic implant (fake heart) that was mentioned in many previous episodes.
Continuity mistake: Near the end of the episode, right after Lore fires the phaser at Dr. Crusher, Data tackles Lore and knocks the phaser out of Lore's hand. The phaser flies towards the cargo transporter and when it impacts, it breaks in two. You can see a piece of it go flying off to the left. Then shortly after when Data throws Lore onto the transporter pad and Lore picks up the phaser, it's in one piece again.
Continuity mistake: When Data and Troi are scanning the list of elements, searching for something to cause an explosion, the list is scrolling "up" the screen. When she tells Data to stop and go back, he does, but the list continues to scroll "up" instead of back "down".
Visible crew/equipment: In the opening scene when Data is portraying a character from Shakespeare's play "The Tempest" a small card can be seen attached to the back of the book he is carrying (likely containing his lines), but after increasing the amount of torch light the card is no longer there.
Continuity mistake: In the beginning of the episode, Riker, Geordi, Worf, Data, and Pulaski are playing poker. Pulaski puts two neat stacks of chips in the center beside some chips in a pile. It then shows Worf putting similar stacks in the center but Pulaski's stacks are not visible and they should be. Then when Worf wins the hand, the camera is showing a wide shot of him pulling the chips towards him and you can see his and Pulaski's neat stacks of chips.
Continuity mistake: Commander Data tells Picard the Saucer Section will arrive in 51 minutes. Riker's synopsis audio can be heard in the background without interruption, and shortly after Data says this, the cameras turn back to Riker and the Video synopsis ends. Riker immediately reports to Picard who then receives the message that the Saucer Section is in orbit. Now, Riker was watching highlights of video footage from the Bridge, of which we see almost all of it because there really wouldn't be that much to view. And that's really all he could watch since we don't have cameras in the "Q-verse" and we see the footage ending with the Q sphere chasing the ship. Also, the entire ordeal was far less than an hour so there's no way a highlight real could take an hour, not to mention the uninterrupted audio. We seem to be missing almost an entire hour.
Other mistake: One of the physical appearances Lal considers adopting is an Andorian female with green skin. In the Trek universe, Andorians invariably have blue skin (the Aenar are a variant of the Andorian race but are depicted with bluish-white skin, still not green). And while other humanoid races have been portrayed with different skin tones, there are some races that have only one skin hue. (ie, Andorians are always blue, Orions are always green, Ferengi are always light orange.) It is highly unlikely she or Data designed it with different skin as Data wants her to fit in, and Troi makes no mention of it.