Continuity: In the scene where Frost has the head pure-blood vampire on the beach, after he pulls out his first vampire tooth you see blood all over his mouth, but when it shows the closeup of him pulling out the other tooth, there is no blood.

Continuity: When Blade gets his serum, Whistler holds his hand, then they see the girl run. In one shot, Whistler goes right, leaving the suffering Blade. In the next shot (close up on Blade), you can see that Whistler is still holding Blade's hand.

Continuity: In the big fight scene in the end between Blade and Frost, the blood smear on Frost's face changes sides a few times.

Continuity: The bloody makeup on Whistler's face and neck changes constantly throughout the scene when he gives his last words.

Continuity: In the shot where Blade knocks the serum down from the wall, he throws one at Frost, then throws five more at him and finally throws the last one in his head. That's seven shots of serum, but when he catches it behind his back there are only six in the pack.

Visible crew/equipment: Near the start when the vampire that's been burnt gets taken into hospital, watch the big glass cabinet as he gets wheeled in by 2 doctors - the crew and the boom mic are reflected in the glass.

Revealing: When Blade uses his booby-trapped sword to knock down the serum from the wall at the end of the movie, you can tell the zoom in of the shot was sped up, as the rotating-timer-thing is spinning quicker than normal, and the screen is vibrating quickly.

Continuity: When Blade is leaving the shop towards the end he fills up 6 phials of EDHD, but he uses 9 phials total. 2 On the 2 people in the hall when he first gets to the building and then 7 more on Deacon at the end.

Revealing: When Karen and Whistler start to fire at Frost's men, after they discovered Blade's hideout, Whistler shoots a black guy who has a large bump under his shirt, quite obviously the squib.

Continuity: When Blade gets captured and stabbed in the room where the "Vampire Bible" is, he is not wearing an ear piece. In the next shot, he is.

Continuity: When Karen tells Blade to take her blood and he does, he eventually releases her and there is just some blood on his bottom jaw. In the next scene, there is blood on his teeth at the top and the bottom.

Continuity: When Blade gets back from the park after meeting with Frost and getting serum, he discovers Frost's men have been there, and sees Whistler. When Blade moves the tape, which is in a metal rotating stand, the stand rotates on its swivel, but in another shot it has only moved a little bit and hasn't rotated either. The tape would've been facing the other direction because the stand swivelled, but instead it remains in the same position.

Continuity: In the House of Erebus, right before Blade jumps off the ledge to fight Frost, you see that Karen is standing on the ledge above everything and Mercury is standing down below on the platform. But when Karen's shooting at her, Mercury is coming down the stairs from above.

Revealing: When Blade is fighting Frost's men near the end, Blade kicks an Asian man to the ground. When he hits the ground, you see he hits some sort of mat or pillow under the dirt.

Continuity: When Karen is telling Blade about the EDTA and the reaction to vampire blood being energetic, in the first shot Karen is putting the bottle of EDTA down on the table, but in the following wider shot she is still holding the bottle.

Continuity: When Blade, Whistler and Karen are talking in Blade's hideout about vampire legends such as stakes and crosses, Whistler takes out the UV torch and is holding it in his right hand, next shot it is in his left hand, then back to his right hand.

Continuity: When Blade Quinn and Karen are in the subway train scene, Karen falls by the train, and Blade offers her his right hand, but in the following shot, it is his left hand he offered to pull her up.

Visible crew/equipment: In the scene near the end of the film when Blade regenerates then kicks vampire butt you can see a man who looks somewhat out of place bouncing up and down in the background.

Continuity: When Blade drops Karen off, she walks to her apartment and as she approaches the elevator a blonde woman walks up to its doors and stops, but in the following shot the blonde woman is now just coming into view and then stands behind the black woman instead of at the elevator doors.

Revealing: When Blade shoots Quinn with a silver like dart, Quinn gets thrown back, and the wall behind Quinn bends when he hits. Then Quinn (stunt double?) bounces off the wall instead of being stapled to it.