Below are a few quotes involving Patrick Dempsey - click the title to view the complete list. If you think their finest moments are missing from the full list, just click "submit something" to submit something new.
Dr. Derek Shepherd: It's not the chase.
Dr. Meredith Grey: What?
Dr. Derek Shepherd: You and me. It is not the thrill of the chase. It's not a game. It's... it's your tiny ineffectual fists. And your hair.
Dr. Meredith Grey: My hair?
Dr. Derek Shepherd: It smells good. And you're very, very ballsy. It keeps me in line.
Dr. Meredith Grey: I'm still not going out with you.
Dr. Derek Shepherd: You say that now.
Dr. Harrison Copeland: What's there to hate?
Julia Fitzpatrick: Nothing, if you're a handsome, divorced doctor, but for the rest of us single women, it's kind of a giant cosmic bitchslap. It's like the universe saying, look, remember when you were fourteen and you had cystic acne and braces and you played the saxophone in the marching band and no one would invite you to the winter formal? Well nothing's changed.
Dr. Harrison Copeland: Oh, I would crawl over cut glass to take you to the winter formal. And then I would prescribe Retin-A for your skin.