Corrected entry: Following the "Large Marge" scene, Pee Wee enters a restaurant with a plaque honoring Large Marge. The dates suggest Marge would have only been 37 at the time of her accident. Alice Nunn would have been 58 at the movie release. The character is portrayed as a woman over 50 years of age.
Other mistake: Five pancakes are made and shot onto the kitchen ceiling, yet only one is on Pee-Wee's plate.
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Suggested correction: I think it's reasonable to presume that one simply fell down onto the plate while the others remained stuck to the ceiling.
Correction: It's a bar, not a restaurant, and if there's a plaque honoring Large Marge it's safe to assume she was a long-time, frequent customer. So you've got years of alcohol use aging her prematurely. Truckers in the 80s were often heavy smokers. So you've got years of tobacco use aging her prematurely. Finally, truckers sit in the sun beating through their windows all day every day. So you've got years of UV light exposure aging her prematurely. Large Marge looked like a trucker in her late 30s-early 40s to me.
Phixius ★