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During the opening credits, Mark Whitacre is writing with his left hand. Later in the film, he's writing with his right. There is no indication that he is ambidextrous, which would properly explain this mistake. See more...
Mark Whitacre: Paranoid is what they call you when they want you to drop your guard.
Mark Whitacre: Polar bears cover their noses before they pounce on a seal. How do polar bears know their noses are black? Did they look in the water one day, see their reflection and say, "Man, I'd be invisible if it wasn't for that thing."