The crewmembers of the Memphis Belle are not based on actual crewmembers. They are fictitious characters.

Very few flyable examples of the B-17 existed at the time of the shooting of the movie. One airplane "stood in" for several by having its decals changed. The B-17G featured in the film has since undergone a meticulous restoration and now lives in Renton, Washington, USA. Though it is fully flyable, certain certification issues with the Federal Aviation Administration have kept it grounded.