Visible crew/equipment: When the police are leaving the motel, you can see a camera reflection in the S.W.A.T. van as it drives by.
Continuity mistake: When Charlie shoots the cow, he had turned off the headlight of the motorcycle. After he shoots the cow the first time, the headlight is back on.
Continuity mistake: Right after Charlie and Irene push the car over the cliff, Charlie asks Irene if she grabbed the wallet off the dash and she says no. Later in the motel, when they are lying in bed, Charlie is sharing family pictures with Irene and they talk about carrying pictures in their wallets. Charlie's was at the bottom of the lake with the car. [The deleted scene on the DVD doesn't really help - in it Hank jumps off the cliff to get his wallet, and then Irene follows. However the movie shows Charlie and Irene looking down the 30 meter high cliff and walking away with dry clothes. Deleted scenes can "disallow" a mistake only if they fill in plausible back story, rather than contradicting the "proper" movie directly.]
Continuity mistake: When Irene and Charlie are in the water near the end, the clouds change between each shot.
Deliberate mistake: When Layla is having babies and the first one comes out there is already a nappy on the baby.
Visible crew/equipment: When Charlie and Irene are driving Irene says 'He did save our lives'. After this it goes to Charlie. Here the boom mic can be seen in the top left of the window.
Continuity mistake: Just as Charlie reaches Dickie and Irene on the bridge, Dickie is looking forward. In the next shot he is looking down and behind him.
Continuity mistake: In the beginning of the movie, when Charlie and Shonté start arguing, Shonté takes his jacket off and throws it to one side. The jacket continually changes sides throughout the scene.
Visible crew/equipment: When Shonte Jr and the boys answer the door to the Colonel, you can see the camera and crew in the reflection of the door.
Revealing mistake: When the baby is pulled out of Layla, you can tell that it's not a newborn baby because he is missing his umbilical cord.
Revealing mistake: After Charlie gets his thumb shot off by Dickey near the end, in most of the shots you can easily see that Charlie is bending his thumb behind the rest of his hand instead of computer graphics removing it.
Revealing mistake: Charlie tells Irene to jump from the moving train when he can't catch up to it. When Irene jumps, the train is standing still. It only appears to be moving because of clever camera manipulation.