Megatron: Is the future of our race not worth a single human life?
Optimus Prime: You'll never stop at one... I'll take you all on!
When Sam is in his bedroom, after he finds the Cube sliver it falls and dramatically burns a hole through the floor into the kitchen. But Sam's bedroom is over the living room (there is nothing on the ground floor below Sam's elevated bathroom, and in the first movie Jazz hides in this open space), and the kitchen is actually located between the den and dining room, at the other end of the house. If they were to follow the actual floor plan of the house, the Cube sliver would have landed in the area of the piano in the living room, but where would the fun have been in that?
Shia LaBeouf's hand was seriously injured during a car accident. LaBeouf returned to filming, and the injury was written into the film as Sam damaging his hand falling out of the space bridge.