Plot hole: Why weren't there guards to prevent Don from entering the quarantined room with Alice and obtaining the Rage virus from her? Even with his master clearance; he wouldn't have the authority to enter such a high risk area unescorted. With the risk of another outbreak from Alice's body fluids, the base commander would have assigned 24-hour guards around her in addition to the forces already in control to ensure no one touched her and became infected. Anything less would have been cause for the commander being relieved for incompetence, assuming he didn't get killed or infected first.

Visible crew/equipment: In the scene where Doyle is talking to the helicopter pilot at the park, you can see another pilot on the left side of Doyle's head for a split second.

Factual error: There is a point where the children travel to their home to get some things. They travel to SOUTH London but as they near their home, look at Canary Wharf in the background! The positioning of the buildings show they are in the EAST towards Dagenham area.

Factual error: The aeroplane lands at London City Airport, although the passengers enter Gatwick Airport.