Deliberate "mistake": Gandu Three Echo, the clone who hits the screen showing the first lottery winner in the movie, complains that he has been around for 7 years and never won the lottery. However, McCord explains later in the movie that the last name tells how old the clones are. Lincoln Six Echo is 3 years old because he is in the Echo generation, and the Delta generation (Jordan Two Delta) is 4 years old. Going backwards, this would make Charlies 5 years old, Bravos 6 years old, and Alphas 7 years old. Gandu Three Echo should have really been Gandu Three Alpha.

Factual error: When the first train wheel hits the ground in the close up, you can see that it isn't made of steel as it deforms as if it were foam. And there is also no damage to the concrete road whatsoever, since the wheels are made of steel there should have been quite a big hole.

Audio problem: When Lincoln 6 Echo is watching the the surgeons kill the other 'product' after giving birth, her heart monitor flat-lines well before the sound does. It beeps about 4 times before the shot changes to a closeup of the flat-line.

Continuity: When the mother is being poisoned shortly after giving birth, we see a toe tag on her right big toe; in the next shot, the toe tag has moved to her left foot.

Visible crew/equipment: At the end of the freeway chase, when Laurent steps out of the passenger side of his car, a camera and several crew members are reflected in the door of an approaching vehicle.

Continuity: When they are driving behind the truck, a flat piece of metal falls off. Shortly before it hits the car it is "flying" horizontal (20°) however in the next shot, when it hits the car it is suddenly vertical (90°). No time between the two shots for that immense change.

Visible crew/equipment: When Sean Bean puts the microbes into Ewan McGregor's eyes, the crew is reflected in his glasses.

Continuity: When Tom and Six-Echo are in the car near the end, the chopper shoots down the traffic lights in front of them. When Six Echo drives off again, he drives straight with no problems.

Continuity: Two members of Laurent's team are in the elevator going up to the 70th floor of a rather tall Gas Company Tower in LA (the building with the giant "R" logo; presumably the building's height has been raised) to go after Lincoln and Jordan. When they step out of the elevator, the display inside says "70," but the floor number outside the elevator says "L," indicating that they're actually on the lobby floor.

Continuity: When the clones are in Lincoln's house he takes a drink. When he picks up the bottle, we see the label, but when starts to drink, the label isn't visible anymore and the time is too short to turn it.

Visible crew/equipment: When Tom Lincoln runs up the stairs to get his shoes and opens the door to his room, you can see a cameraman reflected in the class.

Visible crew/equipment: During the freeway chase, when both the Hummer and the Dodge Magnum are shown flipping over at the same time, the "Bay Buster" camera truck is briefly visible in the background.

Continuity: When Lincoln draws the boat he has been seeing in his dreams, the Renovatio, the sketch he draws has rough lines, and, while appearing complete, it is not finished. Later, the sketch is shown again, but this time it is very detailed, with smooth outlines and shading. Lincoln did not return to finish the drawing at any point. The final sketch looks like it came from an auto-cad program.

Continuity: In the scene with the accelerating fan, there is a shot of the speed dial going towards the maximum. It then cuts to the fan speeding up. When it returns to the dial, the needle traverses the exact same distance that it did before.

Continuity: Towards the beginning of the film, when Lincoln and Jordan first escape, we see them running and hiding in the room full of new 'products'. Water is constantly falling from the ceiling like rain, and both of them are soaked, to the point of water running from their hair and clothing in streams. In the next shot, however, when they have just left the room, they are little more than damp.

Continuity: The Black Wasp shoots out the truck's right front tire, but the subsequent shots show the truck's left front tire blowing out and the right tire intact.

Character mistake: When McCord and Lincoln are talking in the bathroom at the bar, a man walks in on them. McCord calls him "Ed" but the name printed on his shirt is "Lou".

Factual error: As the train axles fall off of the trailer, they move much too rapidly into the vehicles behind the truck. In reality, they would have the same velocity as the truck from which they fell, so, while slowing down from friction, they would continue to roll in the same direction as the traffic.

Continuity: As Lincoln and Jordan are escaping they enter a room and we then see the guards coming down a set of stairs. You then hear Jordan shout at Lincoln. As the camera cuts back, we see the same guard run down the same set of stairs again.

Continuity: When the row of train wheels is first shown rolling off the back of the truck, it has a flat sheet of metal on top of it. In the next shot, the sheet is gone. And in the next shot (when the wheels hit the road), it's back.