Continuity: In the scene where Vic shows Sue the world from the ship, it goes to a shot where Reed finds a problem, when he says "thats impossible it should be 7 hours", The screen show H2 9.44, the next shot it changes to 9.44, the H2 is gone.

Continuity: When the blind woman is leaving the pub, her seeing-eye assistant is bringing her to the door. The woman turns around to say goodbye to The Thing again, her whole body is facing him. When the shot goes to Thing's face & then back to her, she is looking over her shoulder at him.

Continuity: When The Thing gets his pancakes served the butter on top of them change position between shots.

Continuity: After Johnny Storm jumps from the Baxter Building, a close up of him coming from the left is inverted, as seen from the inverted "4" on his chest.

Trivia: Fantastic Four creator (and Marvel editor-in-chief) Stan Lee has a cameo as Willy Lumpkin, the Four's mailman. To date, it's his only Marvel movie cameo based on an actual comic character.