There is a very popular picture advertising this film that shows Emily and Victor reaching their hands toward one another. If you notice, in that particular picture, Emily's bony hand is on her right and Victor's suit and vest are backwards (note its buttons). Some say it was for legal reasons - that Johnny Depp's name was supposed to appear on the poster first because of a contract, and they wanted the characters under the corresponding names, hence the issue. Others say that it was because the picture simply looked better with the bride on the right side. Whatever it is, it's still a very interesting fact about the film.
Audio problem: In the scene where Victor plays the piano for the first time in the movie, we hear him playing long, sustained notes, which obviously need to be played with a pedal down. However, he doesn't use the sustain pedal. What's more strange is, the piano does not even have a sustain pedal.
Deliberate mistake: During the fight scene, the Lord takes an overhead slice at Victor with his sword. Victor catches the blade in the tines of the fork. However, if you look closely, the sword is moves from between the the first and second tine to between the second and third tine.
Continuity mistake: In the scene where Lord Barkis and Victoria are having their wedding feast, all of the guests have been served chicken. But, when the corpses crash the feast, and Bonejangles is standing behind Finis and Maudeline, their chicken has been replaced by soup bowls. ("There's an eye in me soup.")