Peter Fonda meets up with two prostitutes in the film. One is Karen Black and the other Toni Basil who gave us that neat little hit Mickey in 1981.

When Wyatt, Billy and George Hanson enter the diner, all the people in the diner were local inhabitants of that town - none of them were actors. Same for the two rednecks who shoot Wyatt and Billy from their truck, at the end of the film - they weren't actors and that was their pickup truck.

Originally Dennis Hopper didn't want Jack Nicholson in Easy Rider.

Three of the motorcycles used throughout the film were stolen shortly before the film was finished.