In one of the scenes where Steve Martin is talking to the press, one of the reporters is Shawn Levy, this film's director.

The name of Mark's frog is Beans. This is Steven Anthony Lawrence's (who plays Dylan in this film) character's nickname on the Disney channel show, Even Stevens.

Despite playing one of the principal roles as Hank, Ashton Kutcher is not credited in this film.

In the original dozen family there was a girl named Mary Elizabeth Gilbreth. Mary along with some of her other siblings got diphtheria and she, at age 6, was the only one to die from it. The family never got over the loss of Mary and still referred to themselves as the dozen even though all 12 children were never contemporaries. This explains why very few references have Mary's passing in them including the Gilbreth books or even their papers.

In the 1950 version of Cheaper by the Dozen, the father, played by Clifton Webb, dies. Submitted by William Bergquist

When the father is talking to Hilary Duff in her room about the mother not coming home for two weeks music can be heard playing in the background. Listen closely its a song by Hilary duff that she is listening to. Submitted by Spaceboy_007