Trivia: In the casino, while D.J. is fighting with Yosemite Sam's goons, Daffy tells him to "bite his ear." This is a reference to boxer Mike Tyson, who bit off a portion of Evander Holyfield's ear during a match.
Trivia: In Damien Drake's (played by Timothy Dalton) spy car, Bugs is served a martini with a carrot in it. The car says, "Shaken, not stirred." This is how British spy James Bond prefers his martinis, a character Timothy Dalton played in Licence to Kill and The Living Daylights.
Trivia: The monkey that Brendan and Steve get turned into is the same monkey from Bruce Almighty and Ace Ventura.
Trivia: During filming, Brendan Fraser was completely terrified at having to hit Bill Goldberg; Goldberg constantly told him to go ahead and do it, telling him "It's what I do for a living."
Trivia: Michael Jordan's cameo is a reference to Space Jam, starring Michael Jordan and the Looney Tunes.
Trivia: Actor Kevin McCarthy can be found in Area 52 with a pod, in a homage to his role in Invasion of the Body Snatchers (1956). He's even shown in black and white.
Trivia: Whenever something interacts with the Loony Tunes it becomes a cartoon, for example when the film directors get food thrown on them, when DJ trips off the table, and when Daffy is trying to put on the jet pack to become Duck Dodgers.
Trivia: During the "Psycho" shower scene, Bugs Bunny pours a can of chocolate syrup near the drain, and the syrup swirls into the drain. In the original Hitchcock movie "Psycho", chocolate syrup was poured down the shower drain to simulate Janet Leigh's blood going down the drain after she was stabbed by Anthony Perkins.
Trivia: When Damian Drake throws a hand grenade behind him in the "TV in the Painting" scene, a Wilhelm scream can be heard when the grenade explodes.
Answer: It is the cartoon indication of implying someone is a screwball; i.e., a nutcase, or in some other way crazy or out of their mind.
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