Continuity: When Richard Pryor is ramming the police cars after saying "demolition derby", as the shot changes he is not wearing any glasses then he's wearing sunglasses, next shot no glasses, then sunglasses again, then back to none.

Revealing: As the train is approaching the station in "Chicago" in the final scene, the train whips past what is clearly the Royal York Hotel in downtown Toronto. Also, as the crowd is rushing out of the coffee shop in "Union Station in Toronto" the first guy pushing through the door is holding a pack of "Craven A" cigarettes in his hand. Not smokes you would buy in the U.S.

Continuity: At the beginning of the film, when Ned Beatty is hitting on Jill Clayburgh in the bar car, the drink in her glass refills itself from half-full to nearly full.

Continuity: At the end, when the runaway train is going through the garage, you see it approaching the end of the line as indicated by a large "bumper" at the end of the track yet when the shot changes to a front view to see it crashing through, the large "bumper" is gone.

Continuity: Gene Wilder's character has uncoupled the passenger cars from the run away engine. Richard Pryor, who was holding onto Wilder from the front cars, jumps from  the runaway cars to the disconnected cars. If you look closely, you can see a stage hand's arm giving Pryor a push.

Plot hole: In the runaway train scene, Gene Wilder uncouples the train from the forward car, and has to make a dramatic leap to get back to the uncoupled car. Is there any reason he couldn't have uncoupled the train from the back car and just stayed put? It seems an unnecessary bit of drama.

Plot hole: When Gene Wilder is in the bar car lamenting to Ned Beatty about how wrong he's been about everything he is intoxicated. But when Beatty leads Wilder to the top of the train to prove him wrong, Wilder becomes completely sober within a matter of minutes.

Revealing: When George and Grover are driving on the prairie, George points out Kansas City - and the camera pans to a beautiful shot of Calgary, including the unmistakable Calgary Tower.

Factual error: When Richard Kiel is shooting at Gene Wilder on the train, you hear the "ping" of a "silencer" on the gun. However, Kiel is shooting a .357 magnum, which cannot be equipped with a silencer.