Continuity mistake: When Blair asks Mitch "why aren't you answering me?" he says he got a weird message from Laura Barns. Blair replies "that's not funny" and Mitch replies "I'm serious." Then Blair gets a message from Laura, and when she switches back to Mitch's conversation, the last two entries, "that's not funny" and "I'm serious" have disappeared. (00:10:50 - 00:12:30)
Continuity mistake: The bullet hole from Marcus' shot at John's pillow disappears when he rolls over the bed. (00:55:20)
Continuity mistake: When April's lying on the gurney, just as she's wheeled through the doorway it cuts to the closeup as the nurse turns to block Fin from entering the ER, and behind the nurse we see the gurney still being turned and wheeled into the room, but April has vanished.
Continuity mistake: When Harper meets Ryan, who's out jogging in the rain, for the second time to recruit him into the CIA, the hood on Ryan's jacket moves between shots, most noticeably in the very close-up shot of his face. (00:12:00)
Continuity mistake: When Amy kills Desi by slaughtering him, the amount of blood on her left shoulder disappears and reappears, depending on the shot.
Continuity mistake: In the final police chase scene when Lou is getting out of the car to film the car accident, the left hand mirror of his car is intact at first then broken in the next shot.