Continuity mistake: The beginning of the movie is set on Thursday, the day after Jim died, and Bridgette's face was just fine. Later in the movie, on Saturday, Bridgette was at the funeral with cuts and stitches on her face. Then, the movie goes back to Tuesday, the day before Jim died, and they show Bridgette running into the glass door and cutting her face. So if it happened on Tuesday, the first scene of the movie (Thursday) should have shown the cuts on her face.
Continuity mistake: At the start, Robert Neville drives into some yellow poles, only to drive into them again in the following shot.
Continuity mistake: When Amber and Jonesy get an arrow through the head, the cannibal was on Jonesy's side, so the tip should have gone through Amber's head, not Jonesy's.
Continuity mistake: When the car door is ripped off by the cow, it shows the truck with the door intact.
Continuity mistake: The birth of the Predalien in this movie is completely different than it was in the first AVP. The lights on the table are different and the Predalien bursts out differently than in the first film. (00:01:30)
Continuity mistake: The blood stain on Riggs' white shirt around the neck has blood under the collar, then at the end it is over the collar and has increased in amount.
Continuity mistake: When Miroslav is massaging Whitney in the hot springs, the amount of body scrub cream on them drastically changes during shots.
Continuity mistake: As Mike scrolls through the microfilm, we see his view as the pages scroll from right to left. The shot then reverses to show his face through the scrolling film, but while the film is now properly reversed, it's still moving right to left in our view. But this reversed angle should show it moving left to right. (00:12:05)
Continuity mistake: In the beginning, after Michael kills his sisters boyfriend, he puts the mask on with bloody hands yet he gets no blood on the mask.
Continuity mistake: At the beginning, in the scene where Rayne finds two bodies near a small house, she takes out one of her blades. Firstly, she grabs it in a wrong way (the tonfa-like blades should be held under the arm), but when the camera angle changes she holds it properly.
Continuity mistake: After the Zombies are unleashed in the desert scene, we see Carlos crawling under the truck. At first his semi-automatic gun seems to be completely normal. The gun's slide and chamber are closed as if there are still bullets in the magazine or at least one bullet is chambered. But then the camera focuses on his gun and we see the gun's chamber is open - as if there are no bullets left. The gun didn't fire between shots so it's chamber should have been open in the first place. (00:58:10)
Continuity mistake: In the scene where the mother, Denise, is finally beginning to believe their house may be haunted, and is questioning Ben as to whether or not he can see them, Ben points out the window. When Ben points, you can see that the curtain is over the window. When Denise looks back, the curtain is wide open so she can see the barn. When she looks back to Ben, the curtain is again closed.
Continuity mistake: The next morning after they have been attacked, the car windscreen that was smashed is now untouched.
Continuity mistake: In the scene at the dance, where the pumpkin pours cockroaches all over Priscilla, she falls over onto the cake. When she first falls onto the cake, she's just wearing tights and no shoes. In the next shot, she's wearing black shoes.
Continuity mistake: At the beginning of the movie when Jamie leaves his father, his stepmom Ella follows him and his father's head remains in an upright position. However at the end of the movie when Jamie has a flashback of everything that happened, it shows Ella was using his father as a puppet. In the flashback sequence when she lets go of his father to follow Jamie, his father's head automatically drops on his chest and does not remain upright like it did earlier.
Continuity mistake: The amount of sacks by the oven that Laura moves away keeps increasing and decreasing randomly all the time.
Continuity mistake: When the car dies on the side of the road the headlights are off, but when Amy gets out of the car to go with David you catch the headlights shutting off.
Continuity mistake: Mike avoids colliding head-on with a pickup by swerving off the road into a farm field. He does this after passing a tractor and flatbed truck to his right. The shot changes and he is turning off the road into the field between the tractor and truck. (01:36:50)
Continuity mistake: When the guy and girl are sitting in the car, they put the newspaper with duct tape up on the window but later on both the duct tape and newspaper are gone.
Continuity mistake: When the tentacle monster rips out a chunk of Norm's chest, a large spray of blood splashes on his right-side jaw and cheek. In every subsequent shot of him, this blood is gone and his jaws are completely clean. (00:26:30)