Continuity mistake: During "Eyesight to the Blind," The Preacher's guitar changes from a red Les Paul to a black Stratocaster. It's not blatantly obvious, but easy enough to spot without slow-mo. (00:26:33 - 00:30:02)
Revealing mistake: You can see the wires on the handgun pointed at the two extraterrestrial children when the bad guys are staring in shock at the "floating gun."
Continuity mistake: At the very beginning when they are all getting into the yellow Ford car an outside of car camera cut from the front of the car to the side shows the lady's arm firstly inside, then rested on the door.